‘Cells-to-cDNA on Chip’: Phenotypic assessment and gene expression analysis from live cells innanoliter volumes using droplet microarrays  

Dr.S. Chakraborty, C. Luchena, J. J. Elton, Prof. Dr. P. A. Levkin and Dr. A. A. Popova

Adv Healthc Mater., 2022 Mar 14( e2102493)

Droplet microarrays for cell culture: effect of surface properties and nanoliter culture volume on global transcriptomic landscape  

S.Chakraborty, V.Gourain, M.Benz, J.M.Scheiger, P.A.Levkin, A.A.Popova

Materials Today Bio, 2021, 11(100112)

Controlling Geometry and Flow Through Bacterial Bridges on Patterned Lubricant-Infused Surfaces (pLIS)

Wenxi Lei, Peter Krolla, Thomas Schwartz, Pavel A. Levkin

Small, 2020, 16(52)

A combined high-throughput and high-content platform for unified on-chip synthesis, characterization and biological screening

Maximilian Benz, Arndt Asperger, Meike Hamester, Alexander Welle, Stefan Heissler & Pavel A. Levkin 

Nature Communications, 2020, 11(5391)

Assembly of Multi-Spheroid Cellular Architectures by Programmable Droplet Merging

Haijun Cui, Xianxian Wang, Janine Wesslowski, Tina Tronser, Jakob Rosenbauer, Alexander Schug, Gary Davidson, Anna A. Popova, Pavel A. Levkin

Advanced Materials, 2021, 33(4)

Fast Nanoliter-Scale Cell Assays Using Droplet Microarray–Mass Spectrometry Imaging

Carina RamalloGuevara, Dorothea Paulssen, Anna A. Popova, Carsten Hopf, Pavel A. Levkin

Advanced Biology, 2021, 5(3)  


Miniaturized Drug Sensitivity and Resistance Test on Patient-Derived Cells Using Droplet-Microarray

Anna A. Popova, Sascha Dietrich, Wolfgang Huber, Markus Reischl, Ravindra Peravali, Pavel A. Levkin 

SLAS TECHNOLOGY: Translating Life Sciences Innovation 26 (3), August 13, 2020, 274-286   

Droplet‐Microarray: Miniaturized Platform for High‐Throughput Screening of Antimicrobial

Wenxi Lei, Konstantin Demir, Joerg Overhage, Michael Grunze, Thomas Schwarz, Pavel A.Levkin

Advanced Biosystems, October 2020, 2000073

Miniaturized high-throughput synthesis and screening of responsive hydrogels using nanoliter compartments 

A Rosenfeld, C Oelschlaeger, R Thelen, S Heissler, PA Levkin

Materials Today Bio, 2020, 100053

High‐Throughput Screening of Cell Transfection Enhancers Using Miniaturized Droplet Microarrays

Yanxi Liu, Tina Tronser, Ravindra Peravali, Markus Reischl, Pavel A. Levkin

Advanced Biosystems, 11 February 2020, 1900257

Nanomolar Synthesis in Droplet Microarrays with UV-triggered On-Chip Cell Screening

M Brehm, S Heissler, S Afonin, PA Levkin

Small, 20201905971

Solid-phase combinatorial synthesis using microarrays of microcompartments with light-induced on-chip cell screening

Alisa Rosenfeld, Marius Brehm, Alexander Welle, Vanessa Trouillet, Stefan Heissler, Maximilian Benz, Pavel A Levkin

Materials Today Bio, 2019, 100022

Marrying chemistry with biology by combining on-chip solution-based combinatorial synthesis and cellular screening

Maximilian Benz, Mijanur R. Molla, Alexander Böser, Alisa Rosenfeld, Pavel A. Levkin

Nature Communication, 2019, 2879 

Facile One Step Formation and Screening of Tumor Spheroids Using Droplet-Microarray Platform

Anna A Popova, Tina Tronser, Konstantin Demir, P Haitz, Karolina Kuodyte, Vytaute Starkuviene, Piotr Wajda, Pavel A Levkin

Small, 2019, 1901299

Fish-microarray: miniaturized platform for single-embryo high-throughput screenings

Anna A. Popova, Daniel Marcato, Ravindra Peravali, Ilona Wehl, Ute Schepers, and Pavel A. Levkin

Advanced Functional Materials 2017

Droplet Microarray Based on Patterned Superhydrophobic Surfaces Prevents Stem Cell Differentiation and Enables High-Throughput Stem Cell Screening

Tina Tronser, Anna A Popova, Mona Jaggy, Martin Bastmeyer and Pavel A Levkin

Advanced Healthcare Materials 2017, 1700622. 

Biofilm Bridges Forming Structural Networks on Patterned Lubricant-Infused Surfaces 

W Lei, J Bruchmann, JL Rüping, PA Levkin, T Schwartz

Advanced Science, 2019, 1900519

Miniaturized platform for high-throughput screening of stem cells

Tina Tronser, Anna A Popova, and Pavel A Levkin

Current Opinion in Biotechnology
Volume 46, August 2017, Pages 141–149

Patterned SLIPS for the Formation of Arrays of Biofilm Microclusters with Defined Geometries

Julia Bruchmann, Ivana Pini, Tejeshwar S. Gill, Thomas Schwartz, Pavel A. Levkin
Adv. Healthcare Mater.20176, 1601082

Droplet Microarray Based on Superhydrophobic-Superhydrophilic Patterns for Single Cell Analysis

Gabriella E. Jogia, Tina Tronser, Anna A. Popova and Pavel A. Levki

M icroarrays2016, 5, 28

Evaluation of the Droplet-Microarray Platform for High-Throughput Screening of Suspension Cells
Anna A. Popova, Claire Depew, Katya Manuella, Alexander Trubitsyn, Ravindra Peravali, Markus Reischl, and Pavel A. Levkin

Journal of Laboratory Automation 2016

Superhydrophilic–Superhydrophobic Patterned Surfaces as High-Density Cell Microarrays: Optimization of Reverse Transfection

Erica Ueda, Wenqian Feng, and Pavel A. Levkin

Adv. Healthcare Mater. , 2016 5 , 2646–2654

Fabrication of Hydrogel Particles of Defined Shapes Using Superhydrophobic-Hydrophilic Micropatterns 

Ana I. Neto, Konstantin Demir, Anna A. Popova, Mariana B. Oliveira, João F. Mano and Pavel A. Levkin

Adv . Mater . , 2016 28 , 7613–7619

Droplet-Microarray on Superhydrophobic-Superhydrophilic Patterns for High- Throughput Live Cell Screenings

A. A. Popova, K. Demir, T. G. Hartanto, E. Schmitt and P. A. Levkin

RSC Adv., 2016, 6, 38263-38276

Droplet-Array (DA) Sandwich Chip: A Versatile Platform for High-Throughput Cell Screening Based on Superhydrophobic–Superhydrophilic Micropatterning

Anna A. Popova, Sebastian M. Schillo, Konstantin Demir, Erica Ueda, A. Nesterov-Mueller and Pavel A. Levkin

Adv. Mat.201527, 5217-5222