Personalized Medicine: Drug Sensitivity and Resistance Tests
The
field of personalized medicine is rapidly developing area, where the
individual treatment of patient are facilitated by analyzing patient
material in order to come up with individual treatment. A lot of
progress has been done in the field of personal omics profiling.
However, it is not always possible to predict the outcome of the
treatment based on the data obtained in omics profiling. Direct testing
of patient cells with panels of drugs and their combinations is gaining
popularity. One of the example is drug sensitivity and resistant
testing, where tumor cells from patient biopsies are tested against the
combination of anti-neoplastic drugs. The main limitation of this test
is restricted amount of patient material, which is often not enough for
performing big screens. Droplet-Microarray offers a solution for
screenings of minute amount of cells at the same time providing high
throughput allowing for more drugs and combinations to be tested on a
single patient biopsy.